Possible numbers of positive vials after the mixing accident
Here is the patient-to-vial assignment table:
| Patient | Vials | Patient | Vials |
|---|
| 1 | B, D, F, H | 9 | A, D, F, H |
| 2 | B, D, F, G | 10 | A, D, F, G |
| 3 | B, D, E, H | 11 | A, D, E, H |
| 4 | B, D, E, G | 12 | A, D, E, G |
| 5 | B, C, F, H | 13 | A, C, F, H |
| 6 | B, C, F, G | 14 | A, C, F, G |
| 7 | B, C, E, H | 15 | A, C, E, H |
| 8 | B, C, E, G | 16 | A, C, E, G |
Understanding the structure: Each patient's vial-set is a unique 4-vial code — one vial chosen from each of four pairs: (A/B), (C/D), (E/F), (G/H). Two distinct patients always differ in at least one of these four positions.
What the accident does: Two patients' blood is mixed into one combined sample before distribution. That combined sample is placed into every vial that either patient was assigned to — i.e., it reaches the union of the two patients' vial-sets. Exactly one patient has the disease, so we consider two cases.
Case 1 — the diseased patient is NOT one of the two mixed patients.
The disease travels only with the diseased patient's own, unmixed sample. Exactly that patient's 4 vials test positive.
→ 4 positive vials.
Case 2 — the diseased patient IS one of the two mixed patients.
The combined sample carries the disease, so every vial in the union of the two patients' 4-vial sets tests positive. The number of positive vials equals the size of this union.
Since each patient picks one vial from each of the four pairs, two distinct patients share a vial in every position where they make the same choice. If they differ in k of the four positions, they share 4−k vials, so:
Union size=4+4−(4−k)=4+k
| Positions they differ in (k) | Shared vials | Union size |
|---|
| 1 | 3 | 5 |
| 2 | 2 | 6 |
| 3 | 1 | 7 |
| 4 | 0 | 8 |
Every value from 5 to 8 is achievable:
- k=1: patients 1 (B,D,F,H) and 2 (B,D,F,G) differ only in position 4 → union size 5.
- k=2: patients 1 and 4 (B,D,E,G) differ in positions 3 and 4 → union size 6.
- k=3: patients 1 and 8 (B,C,E,G) differ in positions 2, 3, 4 → union size 7.
- k=4: patients 1 (B,D,F,H) and 16 (A,C,E,G) differ in all four positions → union size 8.
Since two distinct patients can never be identical, the union can never be as small as 4 in this case.
Combining both cases:
- Case 1 gives 4 positive vials.
- Case 2 gives 5, 6, 7, or 8 positive vials.
The full set of possible positive-vial counts is:
{4, 5, 6, 7, 8}
Answer: {4, 5, 6, 7, 8} (Choice C).